Extracellular vesicle-derived LINC00511 promotes glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer through macrophage polarization by microRNA-193a-3p-dependent regulation of plasminogen activator urokinase.

Zhang, Tingting; Yu, Hongyang; Bai, Yuxian; Song, Jiaming; Chen, Jiexin; Li, Yingjie; Cui, Yue

Zhang, Tingting; Yu, Hongyang; Bai, Yuxian; Song, Jiaming; Chen, Jiexin; Li, Yingjie; Cui, Yue.

Afiliación

Zhang T; Department of Oncology Internal Medicine, Harbin Medical University Cancer Hospital, Harbin, China.
Yu H; Department of Radiation Oncology, The Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Bai Y; Department of Oncology Internal Medicine, Harbin Medical University Cancer Hospital, Harbin, China.
Song J; Department of Oncology Internal Medicine, Harbin Medical University Cancer Hospital, Harbin, China.
Chen J; Department of Radiation Oncology, The Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Li Y; Department of Radiation Oncology, The Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Cui Y; Department of Radiation Oncology, The Second Affiliated Hospital, Harbin Medical University, Harbin, China.

Immunopharmacol Immunotoxicol ; 45(3): 355-369, 2023 Jun.

Article en En | MEDLINE | ID: mdl-36476048

Asunto(s)

Vesículas Extracelulares; MicroARNs; Neoplasias Pancreáticas; ARN Largo no Codificante; Humanos; Línea Celular Tumoral; Vesículas Extracelulares/genética; Vesículas Extracelulares/metabolismo; Glucólisis; Macrófagos/metabolismo; MicroARNs/genética; MicroARNs/metabolismo; Fosforilación Oxidativa; Neoplasias Pancreáticas/genética; Neoplasias Pancreáticas/metabolismo; Neoplasias Pancreáticas/patología; Activadores Plasminogénicos/metabolismo; Microambiente Tumoral; Activador de Plasminógeno de Tipo Uroquinasa/genética; Activador de Plasminógeno de Tipo Uroquinasa/metabolismo; ARN Largo no Codificante/genética; Neoplasias Pancreáticas

Palabras clave

glycolysis; LINC00511; extracellular vesicles; microRNA-193a-3p; pancreatic cancer; tumor microenvironment

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / MicroARNs / ARN Largo no Codificante / Vesículas Extracelulares Límite: Humans Idioma: En Revista: Immunopharmacol Immunotoxicol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / TOXICOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China

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