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Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity.
Kaserman, Joseph E; Werder, Rhiannon B; Wang, Feiya; Matte, Taylor; Higgins, Michelle I; Dodge, Mark; Lindstrom-Vautrin, Jonathan; Bawa, Pushpinder; Hinds, Anne; Bullitt, Esther; Caballero, Ignacio S; Shi, Xu; Gerszten, Robert E; Brunetti-Pierri, Nicola; Liesa, Marc; Villacorta-Martin, Carlos; Hollenberg, Anthony N; Kotton, Darrell N; Wilson, Andrew A.
Afiliación
  • Kaserman JE; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.
  • Werder RB; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Wang F; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Matte T; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Higgins MI; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Dodge M; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Lindstrom-Vautrin J; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Bawa P; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Hinds A; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.
  • Bullitt E; Department of Physiology and Biophysics, Boston University, Boston, MA 02118, USA.
  • Caballero IS; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Shi X; Division of Cardiovascular Medicine, Beth Israel Deaconess Hospital, Boston, MA 02118, USA.
  • Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Hospital, Boston, MA 02118, USA.
  • Brunetti-Pierri N; Telethon Institute of Genetics and Medicine, 80078 Pozzuoli, Naples, Italy; Department of Translational Medicine, Federico II University, 80131 Naples, Italy.
  • Liesa M; Departments of Medicine, Endocrinology, and Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Institut de Biologia Molecular de Barcelona (IBMB-CSIC), 08028 Barcelona, Catalonia, Spain.
  • Villacorta-Martin C; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA.
  • Hollenberg AN; Joan and Sanford I. Weill Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.
  • Kotton DN; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA.
  • Wilson AA; Center for Regenerative Medicine (CReM) of Boston University and Boston Medical Center, Boston, MA 02118, USA; The Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address: awilson@bu.edu.
Cell Rep ; 41(10): 111775, 2022 12 06.
Article en En | MEDLINE | ID: mdl-36476855
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas Límite: Humans Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas Límite: Humans Idioma: En Revista: Cell Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos