Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells.

Gong, Zheng; Li, Qing; Shi, Jiayuan; Liu, Edison T; Shultz, Leonard D; Ren, Guangwen

Gong, Zheng; Li, Qing; Shi, Jiayuan; Liu, Edison T; Shultz, Leonard D; Ren, Guangwen.

Afiliación

Gong Z; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Li Q; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Shi J; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Liu ET; The Jackson Laboratory for Genomic Medicine, Farmington, CT 06030, USA.
Shultz LD; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Ren G; The Jackson Laboratory, Bar Harbor, ME 04609, USA; Tufts University School of Medicine, Boston, MA 02111, USA; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME 04469, USA. Electronic address: gary.ren@jax.org.

Cell Metab ; 34(12): 1960-1976.e9, 2022 12 06.

Article en En | MEDLINE | ID: mdl-36476935

Asunto(s)

Células Asesinas Naturales; Neoplasias Pulmonares; Animales; Ratones; Pulmón; Lípidos

Palabras clave

IL-1ß; NK cells; breast cancer; disseminated tumor cells; inflammation; lipid storage; lung metastasis; mesenchymal cells; metabolic reprograming; triglycerides

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Asesinas Naturales / Neoplasias Pulmonares Límite: Animals Idioma: En Revista: Cell Metab Asunto de la revista: METABOLISMO Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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