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Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program.
Wheeler, Marsha M; Stilp, Adrienne M; Rao, Shuquan; Halldórsson, Bjarni V; Beyter, Doruk; Wen, Jia; Mihkaylova, Anna V; McHugh, Caitlin P; Lane, John; Jiang, Min-Zhi; Raffield, Laura M; Jun, Goo; Sedlazeck, Fritz J; Metcalf, Ginger; Yao, Yao; Bis, Joshua B; Chami, Nathalie; de Vries, Paul S; Desai, Pinkal; Floyd, James S; Gao, Yan; Kammers, Kai; Kim, Wonji; Moon, Jee-Young; Ratan, Aakrosh; Yanek, Lisa R; Almasy, Laura; Becker, Lewis C; Blangero, John; Cho, Michael H; Curran, Joanne E; Fornage, Myriam; Kaplan, Robert C; Lewis, Joshua P; Loos, Ruth J F; Mitchell, Braxton D; Morrison, Alanna C; Preuss, Michael; Psaty, Bruce M; Rich, Stephen S; Rotter, Jerome I; Tang, Hua; Tracy, Russell P; Boerwinkle, Eric; Abecasis, Goncalo R; Blackwell, Thomas W; Smith, Albert V; Johnson, Andrew D; Mathias, Rasika A; Nickerson, Deborah A.
Afiliación
  • Wheeler MM; Department of Genome Sciences, University of Washington, Seattle, WA, 98105, USA.
  • Stilp AM; Department of Biostatistics, University of Washington, Seattle, WA, 98105, USA.
  • Rao S; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Halldórsson BV; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA.
  • Beyter D; Harvard Stem Cell Institute, Boston, MA, 02138, USA.
  • Wen J; Broad Institute, Cambridge, MA, 02142, USA.
  • Mihkaylova AV; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.
  • McHugh CP; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China.
  • Lane J; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
  • Jiang MZ; School of Technology, Reykjavik University, Reykjavík, Iceland.
  • Raffield LM; deCODE genetics/Amgen Inc., Reykjavik, Iceland.
  • Jun G; Departments of Biostatistics, Genetics, Computer Science, Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Sedlazeck FJ; Department of Biostatistics, University of Washington, Seattle, WA, 98105, USA.
  • Metcalf G; Department of Biostatistics, University of Washington, Seattle, WA, 98105, USA.
  • Yao Y; Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, 55455, USA.
  • Bis JB; Departments of Biostatistics, Genetics, Computer Science, Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Chami N; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA.
  • de Vries PS; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Desai P; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
  • Floyd JS; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
  • Gao Y; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, 02115, USA.
  • Kammers K; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA.
  • Kim W; Harvard Stem Cell Institute, Boston, MA, 02138, USA.
  • Moon JY; Broad Institute, Cambridge, MA, 02142, USA.
  • Ratan A; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.
  • Yanek LR; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, 98101, USA.
  • Almasy L; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Becker LC; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Blangero J; Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Cho MH; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY, 10065, USA.
  • Curran JE; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, 98101, USA.
  • Fornage M; Jackson Heart Study, Department of Medicine, University of Mississippi, Jackson, MS, 39216, USA.
  • Kaplan RC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
  • Lewis JP; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, 2115, USA.
  • Loos RJF; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Mitchell BD; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, 22908, USA.
  • Morrison AC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
  • Preuss M; Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Psaty BM; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
  • Rich SS; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, 78520, USA.
  • Rotter JI; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, 2115, USA.
  • Tang H; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, 78520, USA.
  • Tracy RP; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Boerwinkle E; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
  • Abecasis GR; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Blackwell TW; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Smith AV; Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Johnson AD; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Mathias RA; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Nickerson DA; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.
Nat Commun ; 13(1): 7592, 2022 12 08.
Article en En | MEDLINE | ID: mdl-36481753
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Sanguíneas / Estudio de Asociación del Genoma Completo Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Sanguíneas / Estudio de Asociación del Genoma Completo Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos