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Temporal trends in admissions for atrial fibrillation and severe bleeding in England: an 18-year longitudinal analysis.
Seidu, Samuel; Gillies, Clare; Zaccardi, Francesco; Reeves, Katharine; Gallier, Suzy; Khunti, Kamlesh.
Afiliación
  • Seidu S; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, UK.
  • Gillies C; Real World Evidence Unit, University of Leicester, Leicester, UK.
  • Zaccardi F; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, UK.
  • Reeves K; Real World Evidence Unit, University of Leicester, Leicester, UK.
  • Gallier S; Diabetes Research Centre, Leicester General Hospital, University of Leicester, Leicester, UK.
  • Khunti K; Real World Evidence Unit, University of Leicester, Leicester, UK.
Scand Cardiovasc J ; 57(1): 40-47, 2023 12.
Article en En | MEDLINE | ID: mdl-36519374
ABSTRACT
Objective. Temporal trends in admissions for atrial fibrillation (AF) and severe bleeding associated with AF vary worldwide. We aimed to explore their temporal trends in England and their relation to the introduction of DOACs in 2014 in the UK. Design. This longitudinal ecological study utilised aggregated data that was extracted from the Hospital Episode Statistics database, which captured annual admissions for AF and severe bleeding associated with AF between 2001 and 2018. Trends in admissions over the study period and across age groups, gender and regions in England were assessed. Results. In total, there were 11,292,177 admissions for AF and 324,851 admissions for severe bleeding associated with AF. There was a steady rise in admissions for AF from 2001 to 2017 (204,808 to 1,109,295; p for trend<.001). A similar trend was observed for severe bleeding (4940 to 30,169; p for trend <.001), but the increase dropped slightly between 2013 and 2014 and continued thereafter. Conclusions. There was a rise in admissions for AF and severe bleeding in England between 2001 and 2018. There is little evidence that the slight drop in admissions for severe bleeding between 2013 and 2014 may have been caused by the introduction of DOACs in 2014. Contributors to these trends need urgent exploration.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fibrilación Atrial / Accidente Cerebrovascular Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Scand Cardiovasc J Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fibrilación Atrial / Accidente Cerebrovascular Tipo de estudio: Diagnostic_studies / Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Scand Cardiovasc J Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido