Immunoglobulin D in cerebrospinal fluid.
Clin Chim Acta
; 165(2-3): 289-93, 1987 Jun 15.
Article
en En
| MEDLINE
| ID: mdl-3652450
ABSTRACT
Immunoglobulin D (IgD) was measured by radioimmunoassay in paired cerebrospinal fluid and serum samples from patients with various neurological diseases. The IgD index was calculated for every patient and compared with the IgG index. An increased IgD index was found in 18 out of 41 patients suffering from multiple sclerosis and in 52 out of all 122 patients investigated. An increased IgD index did not always coincide with an increased IgG index. An increased IgD index suggests an abnormal intrathecal synthesis of this immunoglobulin within the central nervous system. We conclude that the determination of IgD in the cerebrospinal fluid yields additional information on immunological reactions within the central nervous system.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Inmunoglobulina D
Límite:
Humans
Idioma:
En
Revista:
Clin Chim Acta
Año:
1987
Tipo del documento:
Article
País de afiliación:
Países Bajos