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Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.
Replogle, Joseph M; Bonnar, Jessica L; Pogson, Angela N; Liem, Christina R; Maier, Nolan K; Ding, Yufang; Russell, Baylee J; Wang, Xingren; Leng, Kun; Guna, Alina; Norman, Thomas M; Pak, Ryan A; Ramos, Daniel M; Ward, Michael E; Gilbert, Luke A; Kampmann, Martin; Weissman, Jonathan S; Jost, Marco.
Afiliación
  • Replogle JM; Medical Scientist Training Program, University of California, San Francisco, San Francisco, United States.
  • Bonnar JL; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
  • Pogson AN; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, United States.
  • Liem CR; Whitehead Institute for Biomedical Research, Cambridge, United States.
  • Maier NK; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
  • Ding Y; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, United States.
  • Russell BJ; Whitehead Institute for Biomedical Research, Cambridge, United States.
  • Wang X; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
  • Leng K; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, United States.
  • Guna A; Whitehead Institute for Biomedical Research, Cambridge, United States.
  • Norman TM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
  • Pak RA; Department of Microbiology, Harvard Medical School, Boston, United States.
  • Ramos DM; Department of Microbiology, Harvard Medical School, Boston, United States.
  • Ward ME; Department of Microbiology, Harvard Medical School, Boston, United States.
  • Gilbert LA; Department of Microbiology, Harvard Medical School, Boston, United States.
  • Kampmann M; Medical Scientist Training Program, University of California, San Francisco, San Francisco, United States.
  • Weissman JS; Institute for Neurodegenerative Disease, University of California, San Francisco, San Francisco, United States.
  • Jost M; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
Elife ; 112022 12 28.
Article en En | MEDLINE | ID: mdl-36576240
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / ARN Guía de Sistemas CRISPR-Cas Tipo de estudio: Guideline Idioma: En Revista: Elife Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / ARN Guía de Sistemas CRISPR-Cas Tipo de estudio: Guideline Idioma: En Revista: Elife Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos