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A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Liu, Zaizhou; Chen, Kaige; Dai, Jun; Xu, Peng; Sun, Wei; Liu, Wanlin; Zhao, Zhixin; Bennett, Steven P; Li, Peifeng; Ma, Tiancheng; Lin, Yuqi; Kawakami, Akinori; Yu, Jing; Wang, Fei; Wang, Chunxi; Li, Miao; Chase, Peter; Hodder, Peter; Spicer, Timothy P; Scampavia, Louis; Cao, Chunyang; Pan, Lifeng; Dong, Jiajia; Chen, Yong; Yu, Biao; Guo, Min; Fang, Pengfei; Fisher, David E; Wang, Jing.
Afiliación
  • Liu Z; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Chen K; School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou, Guangdong, China.
  • Dai J; School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China.
  • Xu P; Department of Dermatology, Cutaneous Biology Research Center, Mass. General Hospital, Harvard Medical School, Boston, MA, USA.
  • Sun W; School of Pharmacy, University of Wisconsin-Madison, Madison, WI, USA.
  • Liu W; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Zhao Z; School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
  • Bennett SP; Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
  • Li P; Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
  • Ma T; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Lin Y; Scripps Research, Jupiter, FL, USA.
  • Kawakami A; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Yu J; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Wang F; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Wang C; Department of Dermatology, Cutaneous Biology Research Center, Mass. General Hospital, Harvard Medical School, Boston, MA, USA.
  • Li M; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Chase P; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Hodder P; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Spicer TP; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Scampavia L; Scripps Research, Jupiter, FL, USA.
  • Cao C; BMS Inc., Lawrenceville, NJ, USA.
  • Pan L; Scripps Research, Jupiter, FL, USA.
  • Dong J; Amgen Inc., Thousand Oaks, CA, USA.
  • Chen Y; Scripps Research, Jupiter, FL, USA.
  • Yu B; Scripps Research, Jupiter, FL, USA.
  • Guo M; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Fang P; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Fisher DE; School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
  • Wang J; State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Cell Res ; 33(1): 55-70, 2023 01.
Article en En | MEDLINE | ID: mdl-36588115
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microftalmía / Melanoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Res Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microftalmía / Melanoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Res Año: 2023 Tipo del documento: Article País de afiliación: China