Optogenetic Low-Frequency Stimulation of Principal Neurons, but Not Parvalbumin-Positive Interneurons, Prevents Generation of Ictal Discharges in Rodent Entorhinal Cortex in an In Vitro 4-Aminopyridine Model.

Proskurina, Elena Y; Chizhov, Anton V; Zaitsev, Aleksey V

Proskurina, Elena Y; Chizhov, Anton V; Zaitsev, Aleksey V.

Afiliación

Proskurina EY; Almazov National Medical Research Centre, 2 Akkuratova Street, 197341 St. Petersburg, Russia.
Chizhov AV; Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, 44 Toreza Prospekt, 194223 St. Petersburg, Russia.
Zaitsev AV; Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences, 44 Toreza Prospekt, 194223 St. Petersburg, Russia.

Int J Mol Sci ; 24(1)2022 Dec 22.

Article en En | MEDLINE | ID: mdl-36613660

Asunto(s)

Corteza Entorrinal; Interneuronas; Animales; Ratones; Ratas; 4-Aminopiridina/farmacología; Corteza Entorrinal/metabolismo; Interneuronas/metabolismo; Optogenética; Parvalbúminas/genética; Parvalbúminas/metabolismo; Ratas Wistar

Palabras clave

4-aminopyridine model; Thy1-ChR2-YFP line 18 mouse; channelrhodopsin; ictal discharge; temporal lobe epilepsy

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Corteza Entorrinal / Interneuronas Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Rusia

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