A study of takotsubo syndrome over 9â¯years at the Tokyo Cardiovascular Care Unit Network Registry.
J Cardiol
; 82(2): 93-99, 2023 08.
Article
en En
| MEDLINE
| ID: mdl-36640906
ABSTRACT
BACKGROUND:
Takotsubo syndrome (TTS) is an acute cardiovascular disease with clinical manifestations similar to those of acute myocardial infarction (AMI), and TTS sometimes occurs just after catastrophes. Large-scale studies of TTS in Japan are scarce, so we examined data over 9â¯years from Tokyo metropolitan acute cardiovascular care hospital network registry.METHODS:
A total of 1626 patients were diagnosed with TTS between 2010 and 2018 at Tokyo Cardiovascular Care Unit Network facilities, and data from all these patients were analyzed. We investigated annual and monthly captured incidence of TTS, temporal trend of the captured incidence proportion of TTS versus AMI, the occurrence of TTS on the day of the great earthquake, and we elucidated the prognostic factors for in-hospital death.RESULTS:
The annual incidence proportion of TTS versus AMI increased from 2.3â¯% to 4.5â¯% (pâ¯<â¯0.001) over 9â¯years. The mean TTS patient age was 74.4â¯years the peak incidence of TTS was at 80 to 84â¯years of age for both male and female; females accounted for 78.5â¯% of patients. The monthly variation of the incidence of TTS was found (pâ¯=â¯0.009). In 2011, a total of 137 cases of TTS occurred, with as many as 6 occurring on March 11, the day of the Great East Japan Earthquake. There was a definable trigger for TTS in 64â¯% (physical 36â¯%; emotional 27â¯%; others 2â¯%). All-cause in-hospital mortality was 5.3â¯% and was higher in males than in females (10.3â¯% vs 3.9â¯%; pâ¯<â¯0.001). Non-cardiac causes accounted for 62â¯% of in-hospital mortality. Factors at presentation that were associated with in-hospital all-cause mortality were male sex, low body mass index, and a high C-reactive protein level.CONCLUSIONS:
This study elucidated the clinical features, in-hospital outcomes, and their attributed factors in patients with TTS in real-world clinical practice in Japan.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cardiomiopatía de Takotsubo
/
Infarto del Miocardio
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
Límite:
Aged
/
Female
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Cardiol
Asunto de la revista:
CARDIOLOGIA
Año:
2023
Tipo del documento:
Article