Stereotactic radiosurgery and combined immune checkpoint therapy with ipilimumab and nivolumab in patients with melanoma brain metastases: A retrospective monocentric toxicity analysis.

Bodensohn, Raphael; Werner, Simone; Reis, Jonas; Pazos Escudero, Montserrat; Kaempfel, Anna-Lena; Hadi, Indrawati; Forbrig, Robert; Manapov, Farkhad; Corradini, Stefanie; Belka, Claus; Theurich, Sebastian; Heinzerling, Lucie; Schlaak, Max; Niyazi, Maximilian

Bodensohn, Raphael; Werner, Simone; Reis, Jonas; Pazos Escudero, Montserrat; Kaempfel, Anna-Lena; Hadi, Indrawati; Forbrig, Robert; Manapov, Farkhad; Corradini, Stefanie; Belka, Claus; Theurich, Sebastian; Heinzerling, Lucie; Schlaak, Max; Niyazi, Maximilian.

Afiliación

Bodensohn R; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Werner S; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Reis J; Institute of Neuroradiology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Pazos Escudero M; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Kaempfel AL; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Hadi I; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Forbrig R; Institute of Neuroradiology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Manapov F; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Corradini S; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Belka C; Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377 Munich, Germany.
Theurich S; German Cancer Consortium (DKTK), Partner Site, Munich, Germany.
Heinzerling L; Department of Medicine III, University Hospital, LMU Munich, Ziemssenstraße 1, 80336 Munich, Germany.
Schlaak M; Department of Dermatology and Allergology, University Hospital, LMU Munich, Frauenlobstraße 9-11, 80337 Munich, Germany.
Niyazi M; Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Ulmenweg 18, 91052 Erlangen, Germany.

Clin Transl Radiat Oncol ; 39: 100573, 2023 Mar.

Article en En | MEDLINE | ID: mdl-36655118

Palabras clave

AE, Adverse events; CTCAE, Common Terminology Criteria for Adverse Events; Checkpoint inhibition; GPA, graded prognostic assessment; IPI, ipilimumab; Intracranial hemorrhage; Ipilimumab; LDH, lactate dehydrogenase; MBM, Melanoma brain metastases; MRI, magnet resonance imaging; NIVO, nivolumab; Nivolumab; OS, overall survival; PFS, progression-free survival; RN, radiation necrosis; Radiation necrosis; SRS, Stereotactic radiosurgery; SRT, Stereotactic radiotherapy; Side effects; Stereotactic radiosurgery

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Clin Transl Radiat Oncol Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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