Dual guide RNA-mediated concurrent C&G-to-T&A and A&T-to-G&C conversions using CRISPR base editors.

Zhao, Yuting; Li, Min; Liu, Jie; Xue, Xiaowen; Zhong, Jingli; Lin, Jianxiang; Ye, Bo; Chen, Jun; Qiao, Yunbo

Zhao, Yuting; Li, Min; Liu, Jie; Xue, Xiaowen; Zhong, Jingli; Lin, Jianxiang; Ye, Bo; Chen, Jun; Qiao, Yunbo.

Afiliación

Zhao Y; Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Li M; Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Liu J; Guangzhou Medical University, Guangzhou 511495, China.
Xue X; Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Zhong J; Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Lin J; Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Ye B; Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China.
Chen J; Department of Endocrinology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Qiao Y; Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.

Comput Struct Biotechnol J ; 21: 856-868, 2023.

Article en En | MEDLINE | ID: mdl-36698964

Palabras clave

C&G-to-T&A and A&T-to-G&C conversions; Dual guide RNAs (gRNAs); Multi-nucleotide variant (MNV); SpRY; TP53

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Comput Struct Biotechnol J Año: 2023 Tipo del documento: Article País de afiliación: China

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