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Low protease activity in B cell follicles promotes retention of intact antigens after immunization.
Aung, Aereas; Cui, Ang; Maiorino, Laura; Amini, Ava P; Gregory, Justin R; Bukenya, Maurice; Zhang, Yiming; Lee, Heya; Cottrell, Christopher A; Morgan, Duncan M; Silva, Murillo; Suh, Heikyung; Kirkpatrick, Jesse D; Amlashi, Parastoo; Remba, Tanaka; Froehle, Leah M; Xiao, Shuhao; Abraham, Wuhbet; Adams, Josetta; Love, J Christopher; Huyett, Phillip; Kwon, Douglas S; Hacohen, Nir; Schief, William R; Bhatia, Sangeeta N; Irvine, Darrell J.
Afiliación
  • Aung A; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Cui A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Maiorino L; Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA, USA.
  • Amini AP; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Gregory JR; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Bukenya M; Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA, USA.
  • Zhang Y; Program in Biophysics, Harvard University, Boston, MA, USA.
  • Lee H; Microsoft Research New England, Cambridge, MA, USA.
  • Cottrell CA; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Morgan DM; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Silva M; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Suh H; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Kirkpatrick JD; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Amlashi P; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.
  • Remba T; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.
  • Froehle LM; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Xiao S; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Abraham W; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Adams J; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Love JC; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Huyett P; Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA, USA.
  • Kwon DS; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Hacohen N; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Schief WR; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.
  • Bhatia SN; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
  • Irvine DJ; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.
Science ; 379(6630): eabn8934, 2023 01 27.
Article en En | MEDLINE | ID: mdl-36701450
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Linfocitos B / Inmunización / Vacunación / Ganglios Linfáticos Límite: Animals / Humans Idioma: En Revista: Science Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endopeptidasas / Linfocitos B / Inmunización / Vacunación / Ganglios Linfáticos Límite: Animals / Humans Idioma: En Revista: Science Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos