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A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion.
Mann, Jake P; Duan, Xiaowen; Patel, Satish; Tábara, Luis Carlos; Scurria, Fabio; Alvarez-Guaita, Anna; Haider, Afreen; Luijten, Ineke; Page, Matthew; Protasoni, Margherita; Lim, Koini; Virtue, Sam; O'Rahilly, Stephen; Armstrong, Martin; Prudent, Julien; Semple, Robert K; Savage, David B.
Afiliación
  • Mann JP; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • Duan X; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • Patel S; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • Tábara LC; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge, United Kingdom.
  • Scurria F; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • Alvarez-Guaita A; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • Haider A; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • Luijten I; Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
  • Page M; New Medicines, UCB Pharma, Slough, United Kingdom.
  • Protasoni M; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge, United Kingdom.
  • Lim K; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • Virtue S; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • O'Rahilly S; Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
  • Armstrong M; UCB Pharma, Chemin du Foriest, Braine l'Alleud, Belgium.
  • Prudent J; Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge, United Kingdom.
  • Semple RK; Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
  • Savage DB; MRC Human Genetics Unit, University of Edinburgh, Edinburgh, United Kingdom.
Elife ; 122023 02 01.
Article en En | MEDLINE | ID: mdl-36722855
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Lipodistrofia Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Elife Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resistencia a la Insulina / Lipodistrofia Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Elife Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido