Phenylephrine-Induced Contraction in Guinea Pig Thoracic Aorta Is Triggered by Stimulation of &#945;1L-Adrenoceptors Functionally Coupled with Store-Operated Ca2+ Channels and Voltage-Dependent Ca2+ Channels.

Obara, Keisuke; Yoshioka, Kento; De Dios Regadera, Montserrat; Matsuyama, Yusuke; Yashiro, Ayano; Miyokawa, Mayumi; Iura, Rumi; Tanaka, Yoshio

Phenylephrine-Induced Contraction in Guinea Pig Thoracic Aorta Is Triggered by Stimulation of α_1L-Adrenoceptors Functionally Coupled with Store-Operated Ca²⁺ Channels and Voltage-Dependent Ca²⁺ Channels.

Obara, Keisuke; Yoshioka, Kento; De Dios Regadera, Montserrat; Matsuyama, Yusuke; Yashiro, Ayano; Miyokawa, Mayumi; Iura, Rumi; Tanaka, Yoshio.

Afiliación

Obara K; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.
Yoshioka K; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.
De Dios Regadera M; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.
Matsuyama Y; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.
Yashiro A; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.
Miyokawa M; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.
Iura R; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.
Tanaka Y; Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University.

Biol Pharm Bull ; 46(2): 309-319, 2023.

Article en En | MEDLINE | ID: mdl-36724959

Asunto(s)

Antagonistas Adrenérgicos alfa; Aorta Torácica; Cobayas; Animales; Fenilefrina/farmacología; Antagonistas Adrenérgicos alfa/metabolismo; Antagonistas Adrenérgicos alfa/farmacología; Tamsulosina/metabolismo; Subunidades alfa de la Proteína de Unión al GTP Gq-G11/metabolismo; Prazosina/farmacología; Verapamilo/farmacología; Verapamilo/metabolismo; ARN Mensajero/metabolismo; Contracción Muscular

Palabras clave

guinea pig thoracic aorta; phenylephrine-induced contraction; receptor-operated Ca2+ channel (ROCC); store-operated Ca2+ channel (SOCC); voltage-dependent Ca2+ channel (VDCC); α1L-adrenoceptor

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aorta Torácica / Antagonistas Adrenérgicos alfa Límite: Animals Idioma: En Revista: Biol Pharm Bull Asunto de la revista: BIOQUIMICA / FARMACOLOGIA Año: 2023 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google