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143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical models.
Xu, Lan-Song; Zheng, Su-Xin; Mei, Liang-He; Yang, Ke-Xin; Wang, Ya-Fang; Zhou, Qiang; Kong, Xiang-Tai; Zheng, Ming-Yue; Jiang, Hua-Liang; Xie, Cheng-Ying.
Afiliación
  • Xu LS; The First Affiliated Hospital of USTC (Anhui Provincial Hospital), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, China.
  • Zheng SX; Drug Discovery and Development Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China.
  • Mei LH; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China.
  • Yang KX; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Wang YF; Suzhou AlphaMa Biotechnology Co., Ltd., Suzhou, 215123, China.
  • Zhou Q; Suzhou Institute of Drug Innovation, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Suzhou, 215123, China.
  • Kong XT; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China.
  • Zheng MY; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Jiang HL; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China.
  • Xie CY; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Acta Pharmacol Sin ; 44(7): 1475-1486, 2023 Jul.
Article en En | MEDLINE | ID: mdl-36725884
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas Proto-Oncogénicas p21(ras) Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas Proto-Oncogénicas p21(ras) Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China