Microbial Dynamics in Newly Diagnosed and Treatment Naïve IBD Patients in the Mediterranean.

Rausch, Philipp; Ellul, Sarah; Pisani, Anthea; Bang, Corinna; Tabone, Trevor; Marantidis Cordina, Claire; Zahra, Graziella; Franke, Andre; Ellul, Pierre

Rausch, Philipp; Ellul, Sarah; Pisani, Anthea; Bang, Corinna; Tabone, Trevor; Marantidis Cordina, Claire; Zahra, Graziella; Franke, Andre; Ellul, Pierre.

Afiliación

Rausch P; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Ellul S; Laboratory of Genomics and Molecular Biomedicine, Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Pisani A; Division of Pediatric Surgery, Department of Surgery, Mater Dei Hospital, Malta.
Bang C; Division of Gastroenterology, Department of Medicine, Mater Dei Hospital, Malta.
Tabone T; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Marantidis Cordina C; Division of Gastroenterology, Department of Medicine, Mater Dei Hospital, Malta.
Zahra G; Department of Microbiology, Mater Dei Hospital, Malta.
Franke A; Molecular Diagnostics, Department of Pathology, Mater Dei Hospital, Malta.
Ellul P; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.

Inflamm Bowel Dis ; 29(7): 1118-1132, 2023 07 05.

Article en En | MEDLINE | ID: mdl-36735955

Treatment-naïve IBD onset patients from Malta show clear differences from healthy microbial communities and an elevated level of community disturbance, although differences between pathologies are only revealed by a network perspective. Furthermore, future IBD treatment is predictable by microbial community characteristics.

Asunto(s)

Colitis Ulcerosa; Enfermedad de Crohn; Microbioma Gastrointestinal; Enfermedades Inflamatorias del Intestino; Humanos; ARN Ribosómico 16S/genética; Microbioma Gastrointestinal/genética; Enfermedad de Crohn/diagnóstico; Enfermedad de Crohn/microbiología; Colitis Ulcerosa/microbiología; Enfermedades Inflamatorias del Intestino/microbiología; Heces/microbiología

Palabras clave

Crohn's disease; biomarker; inflammatory bowel disease; microbiome; treatment naïve; treatment prediction; ulcerative colitis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Colitis Ulcerosa / Enfermedad de Crohn / Microbioma Gastrointestinal Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Inflamm Bowel Dis Asunto de la revista: GASTROENTEROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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