The Roles of Epigenetic Regulation and the Tumor Microenvironment in the Mechanism of Resistance to Systemic Therapy in Hepatocellular Carcinoma.

Oura, Kyoko; Morishita, Asahiro; Hamaya, Sae; Fujita, Koji; Masaki, Tsutomu

Oura, Kyoko; Morishita, Asahiro; Hamaya, Sae; Fujita, Koji; Masaki, Tsutomu.

Afiliación

Oura K; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kita 761-0793, Kagawa, Japan.
Morishita A; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kita 761-0793, Kagawa, Japan.
Hamaya S; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kita 761-0793, Kagawa, Japan.
Fujita K; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kita 761-0793, Kagawa, Japan.
Masaki T; Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, Kita 761-0793, Kagawa, Japan.

Int J Mol Sci ; 24(3)2023 Feb 01.

Article en En | MEDLINE | ID: mdl-36769116

Asunto(s)

Carcinoma Hepatocelular; Quimioembolización Terapéutica; Neoplasias Hepáticas; Humanos; Carcinoma Hepatocelular/tratamiento farmacológico; Carcinoma Hepatocelular/genética; Neoplasias Hepáticas/tratamiento farmacológico; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/patología; Microambiente Tumoral/genética; Epigénesis Genética

Palabras clave

drug resistance; hepatocellular carcinoma; immune checkpoint inhibitor; lenvatinib; molecular target agent; regorafenib; sorafenib; systemic therapy; tumor microenvironment; tyrosine kinase

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quimioembolización Terapéutica / Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies / Screening_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Japón

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