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Establishing the Safe Space via Physiologically Based Biopharmaceutics Modeling. Case Study: Fevipiprant/QAW039.
Kourentas, Alexandros; Gajewska, Monika; Lin, Wen; Dhareshwar, Sundeep S; Steib-Lauer, Caroline; Kulkarni, Swarupa; Hirsch, Stefan; Heimbach, Tycho; Mueller-Zsigmondy, Martin.
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  • Kourentas A; Dissolution & Biopharmaceutics, Analytical Research and Development, Technical Research and Development, Novartis AG, CH-4056, Basel, Switzerland.
  • Gajewska M; Pharmacokinetics Sciences, Translational Medicine, Novartis Institutes for BioMedical Research, Novartis AG, CH-4056, Basel, Switzerland.
  • Lin W; Pharmacokinetics Sciences, Translational Medicine, Novartis Institutes for BioMedical Research, Novartis Pharmaceuticals Corporation, New Jersey, One Health Plaza, East Hanover, 07936, USA.
  • Dhareshwar SS; PK/PD Group, Pharmacokinetics, Dynamics and Metabolism, Sanofi, Bridgewater, NJ, USA.
  • Steib-Lauer C; Global Program Management, Global Drug Development, Novartis Pharmaceuticals Corporation, East Hanover, NJ, 07936, USA.
  • Kulkarni S; Analytical Research and Development, Technical Research and Development, Novartis AG, CH-4056, Basel, Switzerland.
  • Hirsch S; Pharmacokinetics Sciences, Translational Medicine, Novartis Institutes for BioMedical Research, Novartis Pharmaceuticals Corporation, New Jersey, One Health Plaza, East Hanover, 07936, USA.
  • Heimbach T; Global Drug Development, Technical Portfolio and Project Management, Technical Research and Development, Novartis AG, CH-4056, Basel, Switzerland.
  • Mueller-Zsigmondy M; Pharmacokinetics Sciences, Translational Medicine, Novartis Institutes for BioMedical Research, Novartis Pharmaceuticals Corporation, New Jersey, One Health Plaza, East Hanover, 07936, USA.
AAPS J ; 25(1): 25, 2023 02 14.
Article en En | MEDLINE | ID: mdl-36788163
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biofarmacia / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Adult / Humans Idioma: En Revista: AAPS J Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2023 Tipo del documento: Article País de afiliación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Biofarmacia / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Adult / Humans Idioma: En Revista: AAPS J Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2023 Tipo del documento: Article País de afiliación: Suiza