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A novel alkaloid compound, DCZ0358, exerts significant antitumor activity in bortezomib-resistant multiple myeloma cells through inhibition of JAK2/STAT3 pathway.
Zhang, Bibo; Li, Bo; Xie, Yongsheng; Chang, Shuaikang; Xu, Zhijian; Hu, Huifang; Chen, Gege; Zhang, Ting; He, Jun; Wu, Xiaosong; Zhu, Huabin; Lai, Weiming; Song, Dongliang; Lu, Ying; Jia, Xinyan; Zhu, Weiliang; Shi, Jumei.
Afiliación
  • Zhang B; Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
  • Li B; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo 315000, China.
  • Xie Y; CAS Key Laboratory of Receptor Research, Stake Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Chang S; Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
  • Xu Z; Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
  • Hu H; CAS Key Laboratory of Receptor Research, Stake Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Chen G; CAS Key Laboratory of Receptor Research, Stake Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhang T; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • He J; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Wu X; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Zhu H; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Lai W; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Song D; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Lu Y; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Jia X; Department of Hematology, The Affiliated People's Hospital of Ningbo University, Ningbo 315000, China.
  • Zhu W; Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
  • Shi J; CAS Key Laboratory of Receptor Research, Stake Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Acta Biochim Biophys Sin (Shanghai) ; 55(2): 215-224, 2023 Feb 25.
Article en En | MEDLINE | ID: mdl-36815376
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Alcaloides / Mieloma Múltiple / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Biochim Biophys Sin (Shanghai) Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Alcaloides / Mieloma Múltiple / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Biochim Biophys Sin (Shanghai) Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China