Upregulation of galectin-3 in influenza A virus infection promotes viral RNA synthesis through its association with viral PA protein.

Yang, Mei-Lin; Chen, Yi-Cheng; Wang, Chung-Teng; Chong, Hao-Earn; Chung, Nai-Hui; Leu, Chia-Hsing; Liu, Fu-Tong; Lai, Michael M C; Ling, Pin; Wu, Chao-Liang; Shiau, Ai-Li

Yang, Mei-Lin; Chen, Yi-Cheng; Wang, Chung-Teng; Chong, Hao-Earn; Chung, Nai-Hui; Leu, Chia-Hsing; Liu, Fu-Tong; Lai, Michael M C; Ling, Pin; Wu, Chao-Liang; Shiau, Ai-Li.

Afiliación

Yang ML; Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, 1, University Road, Tainan, 701401, Taiwan.
Chen YC; Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi, Taiwan.
Wang CT; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 1, University Road, Tainan, 701401, Taiwan.
Chong HE; Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, 1, University Road, Tainan, 701401, Taiwan.
Chung NH; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 1, University Road, Tainan, 701401, Taiwan.
Leu CH; Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, 1, University Road, Tainan, 701401, Taiwan.
Liu FT; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 1, University Road, Tainan, 701401, Taiwan.
Lai MMC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Ling P; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
Wu CL; Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
Shiau AL; Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, 1, University Road, Tainan, 701401, Taiwan.

J Biomed Sci ; 30(1): 14, 2023 Feb 23.

Article en En | MEDLINE | ID: mdl-36823664

Asunto(s)

Virus de la Influenza A; Gripe Humana; Animales; Humanos; Ratones; Proteínas Virales/genética; Galectina 3/genética; Galectina 3/metabolismo; Regulación hacia Arriba; Gripe Humana/genética; ARN Viral/metabolismo; Virus de la Influenza A/genética; Ribonucleoproteínas/genética; Ribonucleoproteínas/metabolismo; ARN Polimerasa Dependiente del ARN/genética; ARN Polimerasa Dependiente del ARN/metabolismo; Replicación Viral/genética

Palabras clave

Galectin-3; Influenza virus; RNA synthesis; RNA-dependent RNA polymerase; Viral PA; vRNP import

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Virus de la Influenza A / Gripe Humana Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: J Biomed Sci Asunto de la revista: MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Taiwán

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