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An MMP-9 exclusive neutralizing antibody attenuates blood-brain barrier breakdown in mice with stroke and reduces stroke patient-derived MMP-9 activity.
Ji, Yabin; Gao, Qiang; Ma, Yinzhong; Wang, Fang; Tan, Xixi; Song, Dengpan; Hoo, Ruby L C; Wang, Zening; Ge, Xin; Han, Hongjie; Guo, Fuyou; Chang, Junlei.
Afiliación
  • Ji Y; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
  • Gao Q; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450001, China; Department of Neurosurgery, Ts
  • Ma Y; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
  • Wang F; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450001, China.
  • Tan X; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China; Department of Neurology, Yangjiang People's Hospital, Yangjiang 529500, China.
  • Song D; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450001, China.
  • Hoo RLC; State Key Laboratory of Pharmaceutical Biotechnology, Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong 999077, China.
  • Wang Z; Department of Chemical and Environmental Engineering, University of California, Riverside, CA 92521, USA.
  • Ge X; Department of Chemical and Environmental Engineering, University of California, Riverside, CA 92521, USA.
  • Han H; Department of Neurosurgery, Pingdingshan Second People's Hospital, Pingdingshan 467000, China.
  • Guo F; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou 450001, China. Electronic address: chyou666@hotmail.com.
  • Chang J; Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. Electronic address: jl.chang@siat.ac.cn.
Pharmacol Res ; 190: 106720, 2023 04.
Article en En | MEDLINE | ID: mdl-36893823
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Isquemia Encefálica / Accidente Cerebrovascular / Accidente Cerebrovascular Hemorrágico Límite: Animals / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Isquemia Encefálica / Accidente Cerebrovascular / Accidente Cerebrovascular Hemorrágico Límite: Animals / Humans Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China