Silencing of IRF7 ameliorates osteoarthritis by inhibiting chondrocyte pyroptosis via targeting FGF21.

Gong, Bin; He, Meng; Shen, Xiang; Tan, Liming; Zha, Zhengang

Gong, Bin; He, Meng; Shen, Xiang; Tan, Liming; Zha, Zhengang.

Afiliación

Gong B; Department of Bone and Joint Surgery, Institute of Orthopedic Diseases, The First Afliated Hospital, Jinan University, Guangzhou 510630, Guangdong Province, PR China; Department of Orthopedics, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan Province, PR China.
He M; Department of Orthopedics, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan Province, PR China.
Shen X; Department of Orthopedics, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan Province, PR China.
Tan L; Department of Orthopedics, Changsha Hospital of Hunan Normal University, Changsha 410006, Hunan Province, PR China. Electronic address: lm0808gk@163.com.
Zha Z; Department of Bone and Joint Surgery, Institute of Orthopedic Diseases, The First Afliated Hospital, Jinan University, Guangzhou 510630, Guangdong Province, PR China. Electronic address: lm0808gk@163.com.

Cytokine ; 165: 156168, 2023 05.

Article en En | MEDLINE | ID: mdl-36963293

Asunto(s)

MicroARNs; Osteoartritis; Ratones; Animales; Condrocitos/metabolismo; Piroptosis; Factor 7 Regulador del Interferón/metabolismo; Lipopolisacáridos/metabolismo; Osteoartritis/metabolismo; Apoptosis; MicroARNs/metabolismo; Interleucina-1beta/metabolismo

Palabras clave

Chondrocytes; FGF21; IRF7; Osteoarthritis; Pyroptosis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / MicroARNs Límite: Animals Idioma: En Revista: Cytokine Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2023 Tipo del documento: Article

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