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Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets.
Singhal, Pankhuri; Veturi, Yogasudha; Dudek, Scott M; Lucas, Anastasia; Frase, Alex; van Steen, Kristel; Schrodi, Steven J; Fasel, David; Weng, Chunhua; Pendergrass, Rion; Schaid, Daniel J; Kullo, Iftikhar J; Dikilitas, Ozan; Sleiman, Patrick M A; Hakonarson, Hakon; Moore, Jason H; Williams, Scott M; Ritchie, Marylyn D; Verma, Shefali S.
Afiliación
  • Singhal P; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Veturi Y; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Dudek SM; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lucas A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Frase A; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • van Steen K; Department of Human Genetics, Katholieke Universiteit Leuven, ON4 Herestraat 49, 3000 Leuven, Belgium.
  • Schrodi SJ; Laboratory of Genetics, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53706, USA.
  • Fasel D; Columbia University, New York, NY 10027, USA.
  • Weng C; Columbia University, New York, NY 10027, USA.
  • Pendergrass R; Genentech, San Francisco, CA 94080, USA.
  • Schaid DJ; Mayo Clinic, Rochester, MN 55902, USA.
  • Kullo IJ; Mayo Clinic, Rochester, MN 55902, USA.
  • Dikilitas O; Mayo Clinic, Rochester, MN 55902, USA.
  • Sleiman PMA; Children's Hospital of Pennsylvania, Philadelphia, PA 19104, USA.
  • Hakonarson H; Children's Hospital of Pennsylvania, Philadelphia, PA 19104, USA.
  • Moore JH; Department of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
  • Williams SM; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
  • Ritchie MD; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: marylyn@pennmedicine.upenn.edu.
  • Verma SS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: shefali.setiaverma@pennmedicine.upenn.edu.
Am J Hum Genet ; 110(4): 575-591, 2023 04 06.
Article en En | MEDLINE | ID: mdl-37028392
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Epistasis Genética / Estudio de Asociación del Genoma Completo Tipo de estudio: Prognostic_studies País/Región como asunto: Europa Idioma: En Revista: Am J Hum Genet Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Epistasis Genética / Estudio de Asociación del Genoma Completo Tipo de estudio: Prognostic_studies País/Región como asunto: Europa Idioma: En Revista: Am J Hum Genet Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos