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External validation of unsupervised COVID-19 clinical phenotypes and their prognostic impact.
Giacobbe, Daniele Roberto; Di Maria, Emilio; Tagliafico, Alberto Stefano; Bavastro, Martina; Trombetta, Carlo Simone; Marelli, Cristina; Di Meco, Gabriele; Cattardico, Greta; Mora, Sara; Signori, Alessio; Vena, Antonio; Mikulska, Malgorzata; Dentone, Chiara; Bruzzone, Bianca; Bignotti, Bianca; Orsi, Andrea; Robba, Chiara; Ball, Lorenzo; Brunetti, Iole; Battaglini, Denise; Di Biagio, Antonio; Sormani, Maria Pia; Pelosi, Paolo; Giacomini, Mauro; Icardi, Giancarlo; Bassetti, Matteo.
Afiliación
  • Giacobbe DR; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Di Maria E; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Tagliafico AS; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Bavastro M; University Unit of Medical Genetics, Galliera Hospital, Genoa, Italy.
  • Trombetta CS; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Marelli C; Department of Radiology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Di Meco G; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Cattardico G; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Mora S; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Signori A; Hygiene Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Vena A; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Mikulska M; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Dentone C; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Bruzzone B; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Bignotti B; Department of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS), University of Genoa, Genoa, Italy.
  • Orsi A; Section of Biostatistics, Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Robba C; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Ball L; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Brunetti I; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Battaglini D; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Di Biagio A; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Sormani MP; Hygiene Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Pelosi P; Department of Radiology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
  • Giacomini M; Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.
  • Icardi G; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
  • Bassetti M; Hygiene Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Ann Med ; 55(1): 2195204, 2023 12.
Article en En | MEDLINE | ID: mdl-37052252
Hospitalized patients with COVID-19 can be classified into different clinical phenotypes based on their demographic, clinical, radiology, and laboratory featuresIn this study, we externally confirmed the prognostic impact of clinical phenotypes previously identified by Gutierrez-Gutierrez and colleagues in a Spanish cohort of hospitalized patients with COVID-19, and the usefulness of their simplified probabilistic model for phenotypes assignmentThis could indirectly support the validity of both phenotype's development and their extrapolation to other hospitals and countries for management decisions during other possible future viral pandemics.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Ann Med Asunto de la revista: MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Ann Med Asunto de la revista: MEDICINA Año: 2023 Tipo del documento: Article País de afiliación: Italia