Design, synthesis, and biological evaluation of new 2-(4-(methylsulfonyl)phenyl)-<i>N</i>-phenylimidazo[1,2-<i>a</i>]pyridin-3-amine as selective COX-2 inhibitors.

Movahed, Mahsa Azami; Abbasi, Fatemeh Khadem; Rajabi, Mahsa; Abedi, Niusha; Naderi, Nima; Daraei, Bahram; Zarghi, Afshin

Design, synthesis, and biological evaluation of new 2-(4-(methylsulfonyl)phenyl)-N-phenylimidazo[1,2-a]pyridin-3-amine as selective COX-2 inhibitors.

Movahed, Mahsa Azami; Abbasi, Fatemeh Khadem; Rajabi, Mahsa; Abedi, Niusha; Naderi, Nima; Daraei, Bahram; Zarghi, Afshin.

Afiliación

Movahed MA; Department of Pharmaceutical Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abbasi FK; Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Rajabi M; Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abedi N; Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Naderi N; Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Daraei B; Department of Pharmacology and Toxicology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zarghi A; Department of Pharmaceutical Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Med Chem Res ; 32(5): 856-868, 2023.

Article en En | MEDLINE | ID: mdl-37056461

Palabras clave

2-a]pyridine; Antinociceptive activity; Imidazo[1; Molecular modeling; Selective COX-2 inhibitors; Synthesis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Med Chem Res Año: 2023 Tipo del documento: Article País de afiliación: Irán

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