Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.

Li, Lele; Cao, Xin; Huang, Lili; Huang, Xiaobo; Gu, Jiayi; Yu, Xiaoli; Zhu, Yan; Zhou, Yue; Song, Yu; Zhu, Manhui

Li, Lele; Cao, Xin; Huang, Lili; Huang, Xiaobo; Gu, Jiayi; Yu, Xiaoli; Zhu, Yan; Zhou, Yue; Song, Yu; Zhu, Manhui.

Afiliación

Li L; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Cao X; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Huang L; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Huang X; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Gu J; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Yu X; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Zhu Y; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Zhou Y; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Song Y; Department of Ophthalmology, Affiliated Hospital 2 of Nantong University, Nantong, 226001, China.
Zhu M; Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou, 215001, China.

J Cell Mol Med ; 27(10): 1327-1340, 2023 05.

Article en En | MEDLINE | ID: mdl-37070131

Asunto(s)

Neovascularización Coroidal; Células Endoteliales; Anciano; Ratones; Humanos; Animales; Células Endoteliales/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Licopeno/farmacología; beta Catenina/metabolismo; Factor A de Crecimiento Endotelial Vascular/metabolismo; Neovascularización Coroidal/tratamiento farmacológico; Neovascularización Coroidal/etiología; Neovascularización Coroidal/metabolismo; Rayos Láser; Fibrosis; Modelos Animales de Enfermedad; Ratones Endogámicos C57BL

Palabras clave

choroidal neovascularization; choroidal vascular endothelial cells; endothelial to mesenchymal transition; lycopene

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neovascularización Coroidal / Células Endoteliales Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Aged / Animals / Humans Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: China

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