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Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.
Blomberg, Olga S; Kos, Kevin; Spagnuolo, Lorenzo; Isaeva, Olga I; Garner, Hannah; Wellenstein, Max D; Bakker, Noor; Duits, Danique E M; Kersten, Kelly; Klarenbeek, Sjoerd; Hau, Cheei-Sing; Kaldenbach, Daphne; Raeven, Elisabeth A M; Vrijland, Kim; Kok, Marleen; de Visser, Karin E.
Afiliación
  • Blomberg OS; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Kos K; Oncode Institute, Utrecht, The Netherlands.
  • Spagnuolo L; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
  • Isaeva OI; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Garner H; Oncode Institute, Utrecht, The Netherlands.
  • Wellenstein MD; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
  • Bakker N; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Duits DEM; Oncode Institute, Utrecht, The Netherlands.
  • Kersten K; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Klarenbeek S; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Hau CS; Oncode Institute, Utrecht, The Netherlands.
  • Kaldenbach D; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Raeven EAM; Oncode Institute, Utrecht, The Netherlands.
  • Vrijland K; Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands.
  • Kok M; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • de Visser KE; Oncode Institute, Utrecht, The Netherlands.
Oncoimmunology ; 12(1): 2201147, 2023.
Article en En | MEDLINE | ID: mdl-37089449
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Activación de Linfocitos / Linfocitos T Reguladores Límite: Animals / Humans Idioma: En Revista: Oncoimmunology Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Activación de Linfocitos / Linfocitos T Reguladores Límite: Animals / Humans Idioma: En Revista: Oncoimmunology Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos