Untargeted Lipidomic Profiling Reveals Lysophosphatidylcholine and Ceramide as Atherosclerotic Risk Factors in <i>apolipoprotein E</i> Knockout Mice.

Law, Shi-Hui; Chan, Hua-Chen; Ke, Guan-Ming; Kamatam, Swetha; Marathe, Gopal Kedihithlu; Ponnusamy, Vinoth Kumar; Ke, Liang-Yin

Untargeted Lipidomic Profiling Reveals Lysophosphatidylcholine and Ceramide as Atherosclerotic Risk Factors in apolipoprotein E Knockout Mice.

Law, Shi-Hui; Chan, Hua-Chen; Ke, Guan-Ming; Kamatam, Swetha; Marathe, Gopal Kedihithlu; Ponnusamy, Vinoth Kumar; Ke, Liang-Yin.

Afiliación

Law SH; Department of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Chan HC; Department of Medical Laboratory Science, College of Medicine, I-Shou University, Kaohsiung 84001, Taiwan.
Ke GM; Center for Lipid Biosciences, Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Kamatam S; Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan.
Marathe GK; Department of Studies in Biochemistry and Molecular Biology, University of Mysore, Manasagangothri, Mysuru 570006, India.
Ponnusamy VK; Department of Studies in Biochemistry and Molecular Biology, University of Mysore, Manasagangothri, Mysuru 570006, India.
Ke LY; Department of Medicinal and Applied Chemistry, Research Center for Precision Environmental Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.

Int J Mol Sci ; 24(8)2023 Apr 09.

Article en En | MEDLINE | ID: mdl-37108120

Asunto(s)

Aterosclerosis; Lisofosfatidilcolinas; Ratones; Animales; Ratones Noqueados; Ceramidas; Lipidómica; Ratones Endogámicos C57BL; Aterosclerosis/genética; Triglicéridos; Colesterol; Factores de Riesgo; Apolipoproteínas E/genética; Apolipoproteínas

Palabras clave

apolipoprotein E (apoE) knockout; atherosclerosis; atherosclerotic cardiovascular disease (ASCVD); ceramide (CER); cholesteryl ester (CE); lipidomic; lysophosphatidylcholine (LPC); mass spectrometry; triglyceride (TG)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Lisofosfatidilcolinas / Aterosclerosis Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Taiwán

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