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Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer.
Wu, Mary Y; Shepherd, Scott T C; Fendler, Annika; Carr, Edward J; Au, Lewis; Harvey, Ruth; Dowgier, Giulia; Hobbs, Agnieszka; Herman, Lou S; Ragno, Martina; Adams, Lorin; Schmitt, Andreas M; Tippu, Zayd; Shum, Benjamin; Farag, Sheima; Rogiers, Aljosja; O'Reilly, Nicola; Bawumia, Philip; Smith, Callie; Carlyle, Eleanor; Edmonds, Kim; Del Rosario, Lyra; Lingard, Karla; Mangwende, Mary; Holt, Lucy; Ahmod, Hamid; Korteweg, Justine; Foley, Tara; Barber, Taja; Hepworth, Stephanie; Emslie-Henry, Andrea; Caulfield-Lynch, Niamh; Byrne, Fiona; Deng, Daqi; Williams, Bryan; Brown, Michael; Caidan, Simon; Gavrielides, Mike; MacRae, James I; Kelly, Gavin; Peat, Kema; Kelly, Denise; Murra, Aida; Kelly, Kayleigh; O'Flaherty, Molly; Popat, Sanjay; Yousaf, Nadia; Jhanji, Shaman; Tatham, Kate; Cunningham, David.
Afiliación
  • Wu MY; COVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
  • Shepherd STC; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK.
  • Fendler A; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Department of Urology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.
  • Carr EJ; Cell Biology of Infection Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Division of Medicine, University College London, London NW1 2PG, UK.
  • Au L; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK; Department of Medical Oncology, Peter MacCallum Cancer
  • Harvey R; Worldwide Influenza Centre, The Francis Crick Institute, London NW1 1AT, UK.
  • Dowgier G; COVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
  • Hobbs A; COVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
  • Herman LS; COVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
  • Ragno M; COVID Surveillance Unit, The Francis Crick Institute, London NW1 1AT, UK.
  • Adams L; Worldwide Influenza Centre, The Francis Crick Institute, London NW1 1AT, UK.
  • Schmitt AM; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Tippu Z; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK.
  • Shum B; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Melanoma and Kidney Cancer Team, The Institute of Cancer Research, London SW7 3RP, UK.
  • Farag S; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Rogiers A; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • O'Reilly N; Worldwide Influenza Centre, The Francis Crick Institute, London NW1 1AT, UK.
  • Bawumia P; Human Biology Science and Technology Platform, The Francis Crick Institute, London NW1 1AT, UK.
  • Smith C; Human Biology Science and Technology Platform, The Francis Crick Institute, London NW1 1AT, UK.
  • Carlyle E; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Edmonds K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Del Rosario L; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Lingard K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Mangwende M; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Holt L; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Ahmod H; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Korteweg J; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Foley T; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Barber T; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
  • Hepworth S; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
  • Emslie-Henry A; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
  • Caulfield-Lynch N; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
  • Byrne F; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
  • Deng D; Cancer Dynamics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
  • Williams B; School of Life and Medical Sciences, University College London, 235 Euston Road, London NW1 2BU, UK; University College London Hospitals NHS Foundation Trust Biomedical Research Centre, London WC1E 6BT, UK.
  • Brown M; University College London Hospitals NHS Foundation Trust Biomedical Research Centre, London WC1E 6BT, UK; Clinical Research Department, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.
  • Caidan S; Safety, Health & Sustainability, The Francis Crick Institute, London NW1 1AT, UK.
  • Gavrielides M; Scientific Computing Scientific Technology Platform, The Francis Crick Institute, London NW1 1AT, UK.
  • MacRae JI; Metabolomics Scientific Technology Platform, The Francis Crick Institute, London NW1 1AT, UK.
  • Kelly G; Department of Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK.
  • Peat K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Kelly D; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Murra A; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Kelly K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • O'Flaherty M; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Popat S; Lung Unit, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Yousaf N; Lung Unit, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK; Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Jhanji S; Anaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Tatham K; Anaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.
  • Cunningham D; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, SM2 5PT, UK.
Cancer Cell ; 41(5): 821-823, 2023 05 08.
Article en En | MEDLINE | ID: mdl-37116490
ABSTRACT
Wu et al. report that patients with hematologic malignancies have reduced immunity against SARS-CoV-2 Omicron subvariants and Sotrovimab retains neutralizing capacity against all tested Omicron subvariants.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Hematológicas / COVID-19 / Neoplasias Límite: Humans Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Hematológicas / COVID-19 / Neoplasias Límite: Humans Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido