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Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition.
Vo, Tuan; Balderson, Brad; Jones, Kahli; Ni, Guiyan; Crawford, Joanna; Millar, Amanda; Tolson, Elissa; Singleton, Matthew; Kojic, Marija; Robertson, Thomas; Walters, Shaun; Mulay, Onkar; Bhuva, Dharmesh D; Davis, Melissa J; Wainwright, Brandon J; Nguyen, Quan; Genovesi, Laura A.
Afiliación
  • Vo T; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Balderson B; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Jones K; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Ni G; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Crawford J; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Millar A; The University of Queensland Frazer Institute, Translational Research Institute, Woolloongabba, QLD, 4102, Australia.
  • Tolson E; The University of Queensland Frazer Institute, Translational Research Institute, Woolloongabba, QLD, 4102, Australia.
  • Singleton M; The University of Queensland Frazer Institute, Translational Research Institute, Woolloongabba, QLD, 4102, Australia.
  • Kojic M; The University of Queensland Frazer Institute, Translational Research Institute, Woolloongabba, QLD, 4102, Australia.
  • Robertson T; Department of Pathology, Royal Brisbane and Women's Hospital, University of Queensland, Brisbane, QLD, 4029, Australia.
  • Walters S; School of Biomedical Sciences, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Mulay O; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Bhuva DD; Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Davis MJ; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, VIC, 3010, Australia.
  • Wainwright BJ; Faculty of Medicine, South Australian Immunogenomics Cancer Institute, The University of Adelaide, Adelaide, SA, 5000, Australia.
  • Nguyen Q; The University of Queensland Frazer Institute, Translational Research Institute, Woolloongabba, QLD, 4102, Australia.
  • Genovesi LA; Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
Genome Med ; 15(1): 29, 2023 05 01.
Article en En | MEDLINE | ID: mdl-37127652
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Meduloblastoma Límite: Animals / Humans Idioma: En Revista: Genome Med Año: 2023 Tipo del documento: Article País de afiliación: Australia
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Meduloblastoma Límite: Animals / Humans Idioma: En Revista: Genome Med Año: 2023 Tipo del documento: Article País de afiliación: Australia