Energetic <i>vs.</i> entropic stabilization between a Remdesivir analogue and cognate ATP upon binding and insertion into the active site of SARS-CoV-2 RNA dependent RNA polymerase.

Long, Chunhong; Romero, Moises Ernesto; Dai, Liqiang; Yu, Jin

Energetic vs. entropic stabilization between a Remdesivir analogue and cognate ATP upon binding and insertion into the active site of SARS-CoV-2 RNA dependent RNA polymerase.

Long, Chunhong; Romero, Moises Ernesto; Dai, Liqiang; Yu, Jin.

Afiliación

Long C; School of Science, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China.
Romero ME; Department of Chemistry, University of California, Irvine, CA 92697, USA.
Dai L; Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, 325001, China.
Yu J; Department of Chemistry, University of California, Irvine, CA 92697, USA.

Phys Chem Chem Phys ; 25(19): 13508-13520, 2023 May 17.

Article en En | MEDLINE | ID: mdl-37132325

Asunto(s)

COVID-19; SARS-CoV-2; Humanos; SARS-CoV-2/metabolismo; Dominio Catalítico; ARN Viral; Tratamiento Farmacológico de COVID-19; Adenosina Monofosfato/química; Antivirales/química; Adenosina Trifosfato/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Phys Chem Chem Phys Asunto de la revista: BIOFISICA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China

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