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Patient-derived head and neck cancer organoids allow treatment stratification and serve as a tool for biomarker validation and identification.
Millen, Rosemary; De Kort, Willem W B; Koomen, Mandy; van Son, Gijs J F; Gobits, Roán; Penning de Vries, Bas; Begthel, Harry; Zandvliet, Maurice; Doornaert, Patricia; Raaijmakers, Cornelis P J; Geurts, Maarten H; Elias, Sjoerd G; van Es, Robert J J; de Bree, Remco; Devriese, Lot A; Willems, Stefan M; Kranenburg, Onno; Driehuis, Else; Clevers, Hans.
Afiliación
  • Millen R; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands. Electronic address: rosie.millen@roche.com.
  • De Kort WWB; Department of Oral and Maxillofacial Surgery, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Koomen M; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands.
  • van Son GJF; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands; Princess Maxima Center, Utrecht, the Netherlands.
  • Gobits R; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands.
  • Penning de Vries B; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands.
  • Begthel H; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands.
  • Zandvliet M; Department of Clinical Sciences - Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
  • Doornaert P; Department of Radiotherapy, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Raaijmakers CPJ; Department of Radiotherapy, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Geurts MH; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands.
  • Elias SG; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands.
  • van Es RJJ; Department of Oral and Maxillofacial Surgery, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • de Bree R; Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Devriese LA; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Willems SM; Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Pathology, University Medical Center Groningen, Groningen, the Netherlands.
  • Kranenburg O; Utrecht Platform for Organoid Technology (U-PORT), Utrecht Medical Center Utrecht, Utrecht, the Netherlands.
  • Driehuis E; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands. Electronic address: else.driehuis@xilis.nl.
  • Clevers H; Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), Utrecht, the Netherlands. Electronic address: h.clevers@hubrecht.eu.
Med ; 4(5): 290-310.e12, 2023 05 12.
Article en En | MEDLINE | ID: mdl-37178682

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias de Cabeza y Cuello / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Med Año: 2023 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias de Cabeza y Cuello / Antineoplásicos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Med Año: 2023 Tipo del documento: Article