Resin and loading condition screening for effective and robust byproducts removal by anion exchange chromatography: A case study.

Chen, Wei; Wang, Peter K; Liao, Chien-Chun; Li, Yifeng; Wan, Yan

Chen, Wei; Wang, Peter K; Liao, Chien-Chun; Li, Yifeng; Wan, Yan.

Afiliación

Chen W; Technology and Process Development (TPD), WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, China.
Wang PK; Elpiscience Biopharma, Ltd., Building 3, 998 Halei Rd., Pudong, Shanghai, 201203, China.
Liao CC; Elpiscience Biopharma, Ltd., Building 3, 998 Halei Rd., Pudong, Shanghai, 201203, China.
Li Y; Technology and Process Development (TPD), WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, China. Electronic address: li_yifeng@wuxibiologics.com.
Wan Y; Technology and Process Development (TPD), WuXi Biologics, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai, 200131, China. Electronic address: wan_yan_010657@wuxibiologics.com.

Protein Expr Purif ; 210: 106297, 2023 10.

Article en En | MEDLINE | ID: mdl-37209930

Asunto(s)

Resinas de Intercambio Aniónico; Cromatografía por Intercambio Iónico/métodos; Resinas de Intercambio Aniónico/química; Aniones; Cationes/química

Palabras clave

Anion exchange (AEX); Flow through; Ion exchange (IEX); Isoelectric point (pI); Partition coefficient (K(p)); Screening

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Resinas de Intercambio Aniónico Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Protein Expr Purif Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: China

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