BEX1 mediates sorafenib resistance in hepatocellular carcinoma by regulating AKT signaling.

Zhuang, Na; Gu, Zhiyun; Feng, Juan; Chai, Zixuan; Shan, Juanjuan; Qian, Cheng

Zhuang, Na; Gu, Zhiyun; Feng, Juan; Chai, Zixuan; Shan, Juanjuan; Qian, Cheng.

Afiliación

Zhuang N; Research Center for Precision Medicine, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, China.
Gu Z; Research Center for Precision Medicine, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, China.
Feng J; Research Center for Precision Medicine, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, China.
Chai Z; Research Center for Precision Medicine, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, China.
Shan J; Research Center for Precision Medicine, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, China. Electronic address: juanjuansh@gmail.com.
Qian C; Research Center for Precision Medicine, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, China. Electronic address: cqian3184@yahoo.com.cn.

Cell Signal ; 108: 110722, 2023 08.

Article en En | MEDLINE | ID: mdl-37209973

Asunto(s)

Antineoplásicos; Carcinoma Hepatocelular; Neoplasias Hepáticas; Humanos; Carcinoma Hepatocelular/patología; Sorafenib/farmacología; Sorafenib/uso terapéutico; Proteínas Proto-Oncogénicas c-akt/metabolismo; Neoplasias Hepáticas/patología; Resistencia a Antineoplásicos/genética; Línea Celular Tumoral; Antineoplásicos/farmacología; Proliferación Celular; Regulación Neoplásica de la Expresión Génica; Proteínas del Tejido Nervioso/metabolismo

Palabras clave

AKT signaling; BEX1; Hepatocellular carcinoma; Sorafenib resistance

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Signal Año: 2023 Tipo del documento: Article País de afiliación: China

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