E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways.

Huang, Tsung-Teng; Chen, Chuan-Mu; Lin, Song-Shu; Lan, Ying-Wei; Cheng, Hsu-Chen; Choo, Kong-Bung; Wang, Ching-Chiung; Huang, Tse-Hung; Chong, Kowit-Yu

Huang, Tsung-Teng; Chen, Chuan-Mu; Lin, Song-Shu; Lan, Ying-Wei; Cheng, Hsu-Chen; Choo, Kong-Bung; Wang, Ching-Chiung; Huang, Tse-Hung; Chong, Kowit-Yu.

Afiliación

Huang TT; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.
Chen CM; Traditional Herbal Medicine Research Center, Taipei Medical University Hospital, Taipei 11031, Taiwan.
Lin SS; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Lan YW; Graduate Institute of Biomedical Sciences, Division of Biotechnology, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Cheng HC; Department of Life Sciences, Agricultural Biotechnology Center, National Chung Hsing University, Taichung 40227, Taiwan.
Choo KB; The iEGG and Animal Biotechnology Center and the Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung 40227, Taiwan.
Wang CC; Department of Nursing, Chang Gung University of Science and Technology, Taoyuan 33302, Taiwan.
Huang TH; Hyperbaric Oxygen Medical Research Laboratory, Bone and Joint Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan.
Chong KY; Division of Pulmonary Biology, The Perinatal Institute of Cincinnati Children's Research Foundation, Cincinnati, OH 45229, USA.

Int J Mol Sci ; 24(11)2023 May 31.

Article en En | MEDLINE | ID: mdl-37298555

Asunto(s)

Sarcoma; Transducción de Señal; Receptor 2 de Factores de Crecimiento Endotelial Vascular; Animales; Embrión de Pollo; Humanos; Inhibidores de la Angiogénesis/uso terapéutico; Movimiento Celular; Proliferación Celular; Células Endoteliales de la Vena Umbilical Humana/metabolismo; Neovascularización Patológica/tratamiento farmacológico; Neovascularización Patológica/metabolismo; Proteínas Proto-Oncogénicas c-akt/metabolismo; Sarcoma/metabolismo; Receptor 2 de Factores de Crecimiento Endotelial Vascular/metabolismo

Palabras clave

E7050; VEGF; VEGFR2; angiogenesis; multidrug-resistant human uterine sarcoma

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sarcoma / Transducción de Señal / Receptor 2 de Factores de Crecimiento Endotelial Vascular Límite: Animals / Humans Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Taiwán

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