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Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity.
Peterson, Kevin A; Khalouei, Sam; Hanafi, Nour; Wood, Joshua A; Lanza, Denise G; Lintott, Lauri G; Willis, Brandon J; Seavitt, John R; Braun, Robert E; Dickinson, Mary E; White, Jacqueline K; Lloyd, K C Kent; Heaney, Jason D; Murray, Stephen A; Ramani, Arun; Nutter, Lauryl M J.
Afiliación
  • Peterson KA; The Jackson Laboratory, Bar Harbor, Maine, ME, USA.
  • Khalouei S; The Centre for Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
  • Hanafi N; Personalis, Inc. 1330 O'Brien Drive, Menlo Park, CA, USA.
  • Wood JA; The Centre for Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
  • Lanza DG; Mouse Biology Program, University of California Davis, California, CA, USA.
  • Lintott LG; The Jackson Laboratory, Bar Harbor, Maine, ME, USA.
  • Willis BJ; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Seavitt JR; The Centre for Phenogenomics, The Hospital for Sick Children, Toronto, ON, Canada.
  • Braun RE; Mouse Biology Program, University of California Davis, California, CA, USA.
  • Dickinson ME; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • White JK; The Jackson Laboratory, Bar Harbor, Maine, ME, USA.
  • Lloyd KCK; Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA.
  • Heaney JD; The Jackson Laboratory, Bar Harbor, Maine, ME, USA.
  • Murray SA; Mouse Biology Program, University of California Davis, California, CA, USA.
  • Ramani A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Nutter LMJ; The Jackson Laboratory, Bar Harbor, Maine, ME, USA.
Commun Biol ; 6(1): 626, 2023 06 10.
Article en En | MEDLINE | ID: mdl-37301944
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Commun Biol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Commun Biol Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos