Systemic delivery of specific and efficient CRISPR/Cas9 system targeting HPV16 oncogenes using LL-37 antimicrobial peptide in C57BL/6 mice.

Khairkhah, Niloofar; Bolhassani, Azam; Rajaei, Farzad; Najafipour, Reza

Khairkhah, Niloofar; Bolhassani, Azam; Rajaei, Farzad; Najafipour, Reza.

Afiliación

Khairkhah N; Department of Molecular Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Bolhassani A; Department of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, Iran.
Rajaei F; Cellular and Molecular Research Center, Research Institute for Non-communicable Disease, Qazvin University of Medical Sciences, Qazvin, Iran.
Najafipour R; Department of Molecular Medicine, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.

J Med Virol ; 95(7): e28934, 2023 07.

Article en En | MEDLINE | ID: mdl-37403986

Asunto(s)

Sistemas CRISPR-Cas; Papillomavirus Humano 16; Ratones; Animales; Humanos; Papillomavirus Humano 16/genética; Péptidos Antimicrobianos; Ratones Endogámicos C57BL; Oncogenes

Palabras clave

CRISPR/Cas9; LL-37 antimicrobial peptide; gene editing; human papillomavirus; systemic delivery

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Papillomavirus Humano 16 / Sistemas CRISPR-Cas Límite: Animals / Humans Idioma: En Revista: J Med Virol Año: 2023 Tipo del documento: Article País de afiliación: Irán

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