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Targeting macrophagic PIM-1 alleviates osteoarthritis by inhibiting NLRP3 inflammasome activation via suppressing mitochondrial ROS/Cl- efflux signaling pathway.
Zhang, Zhen; Xie, Shujun; Qian, Jin; Gao, Fengqiang; Jin, Wenjian; Wang, Lingqiao; Yan, Lili; Chen, Hao; Yao, Wangxiang; Li, Maoqiang; Wang, Xuepeng; Zhu, Liulong.
Afiliación
  • Zhang Z; Department of Orthopedics Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 31000, Zhejiang, China.
  • Xie S; Department of Translational Medicine Research Center, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Cancer Center, Zhejiang University, 310006, Hangzhou, China.
  • Qian J; Department of Orthopedics Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 31000, Zhejiang, China.
  • Gao F; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Jin W; Department of Hepatobiliary Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, 213000, China.
  • Wang L; Department of Pediatrics, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 31000, Zhejiang, China.
  • Yan L; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Chen H; Department of Orthopedics Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 31000, Zhejiang, China.
  • Yao W; Department of Orthopedics Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 31000, Zhejiang, China.
  • Li M; Department of Orthopedics Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 31000, Zhejiang, China.
  • Wang X; Department of Orthopedics Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 31000, Zhejiang, China.
  • Zhu L; Department of Orthopedics Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, 31000, Zhejiang, China. zhuliulong@zju.edu.cn.
J Transl Med ; 21(1): 452, 2023 07 08.
Article en En | MEDLINE | ID: mdl-37422640
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / Sinovitis Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Transl Med Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / Sinovitis Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Transl Med Año: 2023 Tipo del documento: Article País de afiliación: China