Caspase-9 inhibition confers stronger neuronal and vascular protection compared to VEGF neutralization in a mouse model of retinal vein occlusion.

Avrutsky, Maria I; Chen, Claire W; Lawson, Jacqueline M; Snipas, Scott J; Salvesen, Guy S; Troy, Carol M

Avrutsky, Maria I; Chen, Claire W; Lawson, Jacqueline M; Snipas, Scott J; Salvesen, Guy S; Troy, Carol M.

Afiliación

Avrutsky MI; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Chen CW; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Lawson JM; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States.
Snipas SJ; NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Salvesen GS; NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, United States.
Troy CM; Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States.

Front Neurosci ; 17: 1209527, 2023.

Article en En | MEDLINE | ID: mdl-37449272

Palabras clave

VEGF; caspase-9; cell penetrating peptide; edema; ischemia; neurodegeneration; neurovascular; retinal vein occlusion

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Clinical_trials / Prognostic_studies Idioma: En Revista: Front Neurosci Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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