Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects: Distributions of fitness effects of spontaneous mutations.

Plavskin, Yevgeniy; de Biase, Maria Stella; Ziv, Naomi; Janská, Libuse; Zhu, Yuan O; Hall, David W; Schwarz, Roland F; Tranchina, Daniel; Siegal, Mark

Plavskin, Yevgeniy; de Biase, Maria Stella; Ziv, Naomi; Janská, Libuse; Zhu, Yuan O; Hall, David W; Schwarz, Roland F; Tranchina, Daniel; Siegal, Mark.

Afiliación

Plavskin Y; Center for Genomics and Systems Biology, New York University, New York, NY 10003, USA.
de Biase MS; Department of Biology, New York University, New York, NY 10003, USA.
Ziv N; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin 10115, Germany.
Janská L; Humboldt-Universität zu Berlin, Department of Biology, Berlin 10099, Germany.
Zhu YO; Center for Genomics and Systems Biology, New York University, New York, NY 10003, USA.
Hall DW; Department of Biology, New York University, New York, NY 10003, USA.
Schwarz RF; Current address: Shmunis School of Biomedical and Cancer Research, Tel Aviv University, Ramat Aviv, Israel.
Tranchina D; Center for Genomics and Systems Biology, New York University, New York, NY 10003, USA.
Siegal M; Department of Biology, New York University, New York, NY 10003, USA.

bioRxiv ; 2023 Jul 04.

Article en En | MEDLINE | ID: mdl-37461506

Palabras clave

distribution of fitness effects; evolution; mutation accumulation; mutational load; simple sequence repeats

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: BioRxiv Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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