Cell-free DNA in large B-cell lymphoma: MRD and beyond.
Semin Hematol
; 60(3): 142-149, 2023 07.
Article
en En
| MEDLINE
| ID: mdl-37474409
ABSTRACT
Large B-cell lymphomas (LBCLs) are a strikingly diverse set of diseases, including clinical, biological, and molecular heterogeneity. Despite a wealth of information resolving this heterogeneity in the research setting, applying molecular features routinely in the clinic remains challenging. The advent of circulating tumor DNA (ctDNA) liquid biopsies promises to unlock additional molecular information in the clinic, including mutational genotyping, molecular classification, and minimal residual disease detection. Here, we examine the technologies, applications, and studies exploring the utility of ctDNA in LBCLs.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Linfoma de Células B
/
Ácidos Nucleicos Libres de Células
/
ADN Tumoral Circulante
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Semin Hematol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Canadá