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HPV-associated oropharyngeal Adenosquamous carcinoma with early metastatic disease detected by ctDNA.
Newman, Samantha; Cowart, J Harrison; Omar, Nivin; Martin, Elizabeth; Byrd, J Kenneth.
Afiliación
  • Newman S; Department of Otolaryngology Head and Neck Surgery, Medical College of Georgia at Augusta University, Augusta, GA, United States.
  • Cowart JH; Department of Otolaryngology Head and Neck Surgery, Medical College of Georgia at Augusta University, Augusta, GA, United States.
  • Omar N; Department of Pathology, Medical College of Georgia at Augusta University, Augusta GA, United States.
  • Martin E; Department of Pathology and Lab Medicine, West Virginia University Health Sciences Center, Morgantown, WV, United States.
  • Byrd JK; Department of Otolaryngology Head and Neck Surgery, Medical College of Georgia at Augusta University, Augusta, GA, United States. Electronic address: Ken.byrd@augusta.edu.
Oral Oncol ; 145: 106526, 2023 10.
Article en En | MEDLINE | ID: mdl-37482044
Adenosquamous Carcinoma is a rare, aggresssive variant of squamous cell carcinoma that may HPV-driven in the oropharynx. Although it is reported to behave similar to HPV-related squamous cell carcinoma, the literature is very limited for this disease. We present a case of early T and N stage HPV + adenosquamous carcinoma of the tonsil that metastasized immediately following surgery and adjuvant therapy despite only having microscopic nodal burden. Circulating tumor DNA (ctDNA) was instrumental in recognizing and salvaging metastatic disease early with radiation.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias Orofaríngeas / Neoplasias Primarias Secundarias / Carcinoma Adenoescamoso / Infecciones por Papillomavirus Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Oral Oncol Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Escamosas / Neoplasias Orofaríngeas / Neoplasias Primarias Secundarias / Carcinoma Adenoescamoso / Infecciones por Papillomavirus Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Oral Oncol Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos