Pannexin1 channels in the liver: an open enemy.
Front Cell Dev Biol
; 11: 1220405, 2023.
Article
en En
| MEDLINE
| ID: mdl-37492223
ABSTRACT
Pannexin1 proteins form communication channels at the cell plasma membrane surface, which allow the transfer of small molecules and ions between the intracellular compartment and extracellular environment. In this way, pannexin1 channels play an important role in various cellular processes and diseases. Indeed, a plethora of human pathologies is associated with the activation of pannexin1 channels. The present paper reviews and summarizes the structure, life cycle, regulation and (patho)physiological roles of pannexin1 channels, with a particular focus on the relevance of pannexin1 channels in liver diseases.
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Front Cell Dev Biol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Bélgica