Demethylzeylasteral targets lactate to suppress the tumorigenicity of liver cancer stem cells: It is attributed to histone lactylation?

Gong, Hang; Xu, Hui-Mei; Ma, Yao-Hui; Zhang, De-Kui

Gong, Hang; Xu, Hui-Mei; Ma, Yao-Hui; Zhang, De-Kui.

Afiliación

Gong H; Department of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.
Xu HM; Department of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.
Ma YH; Department of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.
Zhang DK; Department of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China. Electronic address: zhangdk8616@126.com.

Pharmacol Res ; 194: 106869, 2023 08.

Article en En | MEDLINE | ID: mdl-37517563

Asunto(s)

Ácido Láctico; Neoplasias; Histonas; Hígado; Células Madre Neoplásicas

Palabras clave

Glycolysis; Histone lactylation; Lactate; Liver cancer; Tumorigenicity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Láctico / Neoplasias Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China

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