Data-driven large-scale genomic analysis reveals an intricate phylogenetic and functional landscape in J-domain proteins.

Malinverni, Duccio; Zamuner, Stefano; Rebeaud, Mathieu E; Barducci, Alessandro; Nillegoda, Nadinath B; De Los Rios, Paolo

Malinverni, Duccio; Zamuner, Stefano; Rebeaud, Mathieu E; Barducci, Alessandro; Nillegoda, Nadinath B; De Los Rios, Paolo.

Afiliación

Malinverni D; Department of Structural Biology and Center for Data Driven Discovery, St. Jude Children's Research Hospital, Memphis, TN 38105.
Zamuner S; Institute of Physics, School of Basic Sciences, École Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland.
Rebeaud ME; Institute of Physics, School of Basic Sciences, École Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland.
Barducci A; Centre de Biologie Structurale, Université de Montpellier, CNRS, INSERM, Montpellier, France.
Nillegoda NB; Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC 3800, Australia.
De Los Rios P; Centre for Dementia and Brain Repair at the Australian Regenerative Medicine Institute, Monash University, Melbourne, VIC 3800, Australia.

Proc Natl Acad Sci U S A ; 120(32): e2218217120, 2023 08 08.

Article en En | MEDLINE | ID: mdl-37523524

Asunto(s)

Proteínas HSP70 de Choque Térmico; Chaperonas Moleculares; Humanos; Secuencia de Aminoácidos; Genómica; Proteínas del Choque Térmico HSP40/metabolismo; Proteínas HSP70 de Choque Térmico/metabolismo; Chaperonas Moleculares/metabolismo; Filogenia

Palabras clave

Hsp40 co-chaperones; J-domain proteins; artificial neural networks; large-scale data analysis; protein homeostasis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Chaperonas Moleculares / Proteínas HSP70 de Choque Térmico Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article

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