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Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram, Kayvon; Shon, D Judy; Tender, Gabrielle S; Mantuano, Natalia R; Northey, Jason J; Metcalf, Kevin J; Wisnovsky, Simon P; Riley, Nicholas M; Forcina, Giovanni C; Malaker, Stacy A; Kuo, Angel; George, Benson M; Miller, Caitlyn L; Casey, Kerriann M; Vilches-Moure, José G; Ferracane, Michael J; Weaver, Valerie M; Läubli, Heinz; Bertozzi, Carolyn R.
Afiliación
  • Pedram K; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
  • Shon DJ; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
  • Tender GS; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
  • Mantuano NR; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
  • Northey JJ; Cancer Immunotherapy Laboratory, Department of Biomedicine, University of Basel, Basel, Switzerland.
  • Metcalf KJ; Division of Oncology, Department of Theragnostics, University Hospital, Basel, Switzerland.
  • Wisnovsky SP; Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California, San Francisco (UCSF), San Francisco, CA, USA.
  • Riley NM; Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California, San Francisco (UCSF), San Francisco, CA, USA.
  • Forcina GC; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
  • Malaker SA; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
  • Kuo A; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
  • George BM; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
  • Miller CL; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
  • Casey KM; Department of Chemistry, Yale University, New Haven, CT, USA.
  • Vilches-Moure JG; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
  • Ferracane MJ; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Weaver VM; Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • Läubli H; Brigham and Women's Hospital, Boston, MA, USA.
  • Bertozzi CR; Department of Chemistry and Sarafan ChEM-H, Stanford University, Stanford, CA, USA.
Nat Biotechnol ; 42(4): 597-607, 2024 Apr.
Article en En | MEDLINE | ID: mdl-37537499

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Mucinas / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Mucinas / Neoplasias Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Nat Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos