New kids on the block: FOS and FOSB gene.
J Clin Pathol
; 76(11): 721-726, 2023 Nov.
Article
en En
| MEDLINE
| ID: mdl-37553246
ABSTRACT
FOS and FOSB proto-oncogens are involved in a wide variety of tumourigenic processes. FOS and FOSB gene rearrangements are observed in epithelioid haemangioma, pseudomyogenic haemangioendothelioma, osteoid osteoma/osteoblastoma/cementoblastoma and proliferative myositis/fasciitis. In this review, we provide an overview of FOS and FOSB, including their functions and the differences between lesions with known FOS/FOSB gene rearrangements. Additionally, we discuss the use of FOS/FOSB immunohistochemistry as a diagnostic tool for these lesions.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proteínas Proto-Oncogénicas c-fos
Límite:
Humans
Idioma:
En
Revista:
J Clin Pathol
Año:
2023
Tipo del documento:
Article
País de afiliación:
Bélgica