Dynamics of the Second Extracellular Loop Control Transducer Coupling of Peptide-Activated GPCRs.

Wygas, Marcel M; Laugwitz, Jeannette M; Schmidt, Peter; Elgeti, Matthias; Kaiser, Anette

Wygas, Marcel M; Laugwitz, Jeannette M; Schmidt, Peter; Elgeti, Matthias; Kaiser, Anette.

Afiliación

Wygas MM; Faculty of Life Sciences, Institute of Biochemistry, Leipzig University, Brüderstr. 34, 04103 Leipzig, Germany.
Laugwitz JM; Medical Faculty, Institute of Medical Physics and Biophysics, Leipzig University, Haertelstasse 16-18, 04107 Leipzig, Germany.
Schmidt P; Medical Faculty, Institute of Medical Physics and Biophysics, Leipzig University, Haertelstasse 16-18, 04107 Leipzig, Germany.
Elgeti M; Medical Faculty, Institute of Medical Physics and Biophysics, Leipzig University, Haertelstasse 16-18, 04107 Leipzig, Germany.
Kaiser A; Medical Faculty, Institute for Drug Discovery, Leipzig University, Haertelstasse 16-18, 04107 Leipzig, Germany.

Int J Mol Sci ; 24(15)2023 Jul 30.

Article en En | MEDLINE | ID: mdl-37569573

Asunto(s)

Péptidos; Rodopsina; Rodopsina/metabolismo; Ligandos; Mutación; Unión Proteica; Péptidos/metabolismo; Disulfuros/química; Receptores Acoplados a Proteínas G/metabolismo

Palabras clave

arrestin; conserved disulfide; electron paramagnetic resonance (EPR); extracellular loop; functional selectivity; peptide G-protein-coupled receptor (GPCR)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Rodopsina Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Alemania

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