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One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids.
Geurts, Maarten H; Gandhi, Shashank; Boretto, Matteo G; Akkerman, Ninouk; Derks, Lucca L M; van Son, Gijs; Celotti, Martina; Harshuk-Shabso, Sarina; Peci, Flavia; Begthel, Harry; Hendriks, Delilah; Schürmann, Paul; Andersson-Rolf, Amanda; Chuva de Sousa Lopes, Susana M; van Es, Johan H; van Boxtel, Ruben; Clevers, Hans.
Afiliación
  • Geurts MH; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT, Utrecht, the Netherlands. M.H.Geurts-6@prinsesmaximacentrum.nl.
  • Gandhi S; Oncode Institute, 3521AL, Utrecht, the Netherlands. M.H.Geurts-6@prinsesmaximacentrum.nl.
  • Boretto MG; Princess Maxima Center for Pediatric Oncology, 3584 CS, Utrecht, the Netherlands. M.H.Geurts-6@prinsesmaximacentrum.nl.
  • Akkerman N; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT, Utrecht, the Netherlands.
  • Derks LLM; Miller Institute for Basic Research in Science, University of California, Berkeley, CA, 94720, USA.
  • van Son G; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT, Utrecht, the Netherlands.
  • Celotti M; Oncode Institute, 3521AL, Utrecht, the Netherlands.
  • Harshuk-Shabso S; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT, Utrecht, the Netherlands.
  • Peci F; Oncode Institute, 3521AL, Utrecht, the Netherlands.
  • Begthel H; Oncode Institute, 3521AL, Utrecht, the Netherlands.
  • Hendriks D; Princess Maxima Center for Pediatric Oncology, 3584 CS, Utrecht, the Netherlands.
  • Schürmann P; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT, Utrecht, the Netherlands.
  • Andersson-Rolf A; Oncode Institute, 3521AL, Utrecht, the Netherlands.
  • Chuva de Sousa Lopes SM; Princess Maxima Center for Pediatric Oncology, 3584 CS, Utrecht, the Netherlands.
  • van Es JH; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT, Utrecht, the Netherlands.
  • van Boxtel R; Oncode Institute, 3521AL, Utrecht, the Netherlands.
  • Clevers H; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT, Utrecht, the Netherlands.
Nat Commun ; 14(1): 4998, 2023 08 17.
Article en En | MEDLINE | ID: mdl-37591832

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Adultas / ARN Guía de Sistemas CRISPR-Cas Límite: Adult / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Adultas / ARN Guía de Sistemas CRISPR-Cas Límite: Adult / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos